Avvio Microbubble SonoLithotripsy

The Avvio Microbubble SonoLithotripsy System combines several cutting-edge technologies to offer a more efficient alternative to traditional methods. At the heart of our system is microbubble cavitation, which uses low-intensity ultrasound energy and our patented  microbubbles to break down ureteral stones with minimal force, unlike the more traumatic shock waves used in conventional treatments.

The Avvio Microbubble SonoLithotripsy System advances ureteral stone treatment by offering a more accessible solution and expanding access to care.

At the core of our system is the ultrasound-induced cavitation of our patented microbubbles which fragments ureteral stones with precision. This method uses lipid microbubbles that are designed to collect on the surface of the stone – a technology that enhances the cavitation process for more efficient and controlled stone erosion. Unlike traditional shock wave therapy, which uses high-pressure waves, our system delivers low-intensity ultrasound, potentially reducing the risk of trauma to surrounding tissues.

Calcium-seeking microbubbles are actuated by the system’s low-intensity ultrasound causing them to cavitate and break down stones into smaller fragments.

The Avvio Console is the heart of the system, providing clinicians with real-time oversight and intuitive control of all components. It seamlessly integrates with the microbubble actuation and the smart ureteral catheter, allowing the operator to monitor the procedure and make adjustments as necessary. The console features an easy-to-use interface that displays real-time feedback on catheter positioning and stone treatment progress.

The console enables precise management of the procedure, enhancing clinician confidence and efficiency. It also streamlines the workflow by consolidating all controls into one device, reducing the need for multiple machines or complex setups.

The treatment head is a unique phased-array transducer designed to emit and steer a beam of low-intensity focused ultrasound spanning approximately 6 cm of ureteral length. Steering the focused beam over 6 cm reduces the need for precise focusing on the target stone.

The reduced acoustic pressure minimizes the need for general anesthesia, offering a less painful, less invasive treatment with a faster recovery time.

The smart ureteral catheter is equipped with acoustic sensors that detect the energy waves in real-time. The signals are received and interpreted by the console and allow the user to precisely locate the catheter and position the treatment head on the patient’s skin. This advanced technology ensures that the treatment head is always in the correct position enhancing the accuracy of the treatment.

This advanced technology ensures that the treatment head is always in the correct position enhancing the accuracy of the treatment.