A Revolutionary New Treatment of
Ureteral Stones

No Routine Anesthesia or Stents.

Breaking the barrier to rapid treatment access.

At Avvio Medical, we are transforming the standard of care for urinary stone disease with a cutting-edge, outpatient procedure that reduces wait times and eliminates the need for routine stents or general anesthesia.

Avvio’s innovative technology uses low-intensity ultrasound to actuate our patented microbubbles, which accumulate near the stone. When actuated by low-intensity ultrasound, the microbubbles cavitate, breaking the stone into smaller particles that can pass spontaneously.

Avvio Microbubble SonoLithotripsy is designed to be gentle and effective and provides timely access to care for patients with ureteral stones.

Bench demonstration of synthetic stone comminution using microbubbles and low-pressure ultrasound.

Minimally Invasive

Our outpatient procedure eliminates the need for routine anesthesia or stents.

Timely Access

Faster access to treatment minimizes the need for pre-op stenting and related complications.

Expanded Access

By eliminating the need for anesthesia and stents, procedures can be done in outpatient clinics or rural settings, reducing the need for specialized facilities.

Cost-Effective

The tissue-sparing technology significantly reduces post-op stenting, anesthesia, and overall medical costs.

See how it works

Avvio Microbubble SonoLithotripsy vs Conventional Care

Avvio has the potential to accelerate stone care from weeks to days – avoiding delays, stents, and general anesthesia. The goal: to help patients get faster, simpler treatment with fewer steps and less disruption. 

With Avvio LithotripsyDay 1ER VisitNon contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsDay 3Urologist ConsultationFollow-upIntervention

Seen by urologist AVVIO Microbubbles Cavitation LithotripsyDay 33Follow-Up VisitAssessment
 Post Procedure check in and CT imaging if neededCurrent Standard of CareDay 1ER VisitNon contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsDay 3Urologist ConsultationSeen by urologist Schedule ureteral stent placementFollow-up
Prescriptions Antibiotics if infection suspected Scheduling
Day 7Stent Placement~ 30 minutes Recovery and dischargeUreteral stent placed under sedation or anesthesia in ASC Procedure
General anesthesia Duration
Post-Procedure Care
Day 45URS-LL1 hour Stent RemovalGeneral anesthesia Duration
Post-Procedure
Day 48Follow-up VisitPost-operative check for complications KUB to confirm stone fragments clearanceAssessment
Imaging 
Day 75Follow-up CT ScanNon-contrast CT scan for stone-free status Evaluation of residual fragments and ureteral healingImaging
Assessment With Avvio LithotripsyDay 1ER VisitNon contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsDay 3Urologist ConsultationFollow-upIntervention

Seen by urologist AVVIO Microbubbles Cavitation LithotripsyDay 33Follow-Up VisitAssessment
 Post Procedure check in and CT imaging if neededCurrent Standard of CareDay 1ER VisitNon contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsDay 3Urologist ConsultationSeen by urologist Schedule ureteral stent placementFollow-up
Prescriptions Antibiotics if infection suspected Scheduling
Day 7Stent Placement~ 30 minutes Recovery and dischargeUreteral stent placed under sedation or anesthesia in ASC Procedure
General anesthesia Duration
Post-Procedure Care
Day 45URS-LL1 hour Stent RemovalGeneral anesthesia Duration
Post-Procedure
Day 48Follow-up VisitPost-operative check for complications KUB to confirm stone fragments clearanceAssessment
Imaging 
Day 75Follow-up CT ScanNon-contrast CT scan for stone-free status Evaluation of residual fragments and ureteral healingImaging
Assessment

News & Events

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*Data on file
CAUTION – Investigational device. Limited by Federal (or United States) law to investigational use. Avvio Medical, Inc. does not currently offer medical devices for sale or distribution and the company’s technology has not received market clearance status by the U.S. FDA or any other country’s regulatory authority.
MKT-0006-01, Rev R, May 2026