A Revolutionary Kidney Stone Treatment

No Anesthesia. No Stents.

Breaking the barrier to rapid treatment access.

At Avvio Medical, we are transforming the standard of care for urinary stone disease with a cutting-edge, office-based procedure that reduces wait times and eliminates the need for stents or general anesthesia.

Our innovative technology uses low-pressure ultrasound to activate calcium-seeking microbubbles, creating millions of micro-jets that break down stones. This approach aims to not only enhance patient safety and comfort but also lowers overall medical costs, offering a more accessible solution for stone treatment.

Bench demonstration of synthetic stone comminution using microbubbles and low-pressure ultrasound. 
Accelerated time-lapse of actual treatment.

Minimally Invasive

Our office-based procedure eliminates the need for general anesthesia or stents.

Faster Treatment

Shorter wait times streamline care, allowing for quicker stone passage and patient recovery.

Expanded Access

By eliminating the need for anesthesia and stents, procedures can be done in outpatient clinics or rural settings, reducing the need for specialized facilities.

Cost-Effective

The procedure reduces overall medical costs by avoiding stenting and anesthesia.

See how it works

Avvio Lithotripsy VS Current Standard of Care

AVVIO has the potential to accelerate stone care from weeks to days – avoiding delays, stents, and general anesthesia. The goal: to help patients get faster, simpler treatment with fewer steps and less disruption. 

With Avvio LithotripsyER VisitDay 1 Non contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsSeen by urologist AVVIO Microbubbles Cavitation LithotripsyFollow-up
Intervention
Assessment Post Procedure check in and CT imaging if neededUrologist ConsultationDay 3 Follow-Up VisitDay 33 Current Standard of CareER VisitDay 1 Non contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsSchedule ureteral stent placementSeen by urologist Follow-up
Prescriptions Antibiotics if infection suspected Scheduling
~ 30 minutes Recovery and dischargeUreteral stent placed under sedation or anesthesia in ASC Procedure
General anesthesia Duration
Post-Procedure Care
1 hour Stent RemovalGeneral anesthesia Duration
Post-Procedure
Post-operative check for complications KUB to confirm stone fragments clearanceAssessment
Imaging 
Non-contrast CT scan for stone-free status Evaluation of residual fragments and ureteral healingImaging
Assessment Urologist ConsultationDay 3 Stent PlacementDay 7 URS-LLDay 45 Follow-up VisitDay 48 Follow-up CT ScanDay 75 With Avvio LithotripsyDay 1ER VisitNon contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsDay 3Urologist ConsultationFollow-upIntervention

Seen by urologist AVVIO Microbubbles Cavitation LithotripsyDay 33Follow-Up VisitAssessment
 Post Procedure check in and CT imaging if neededCurrent Standard of CareDay 1ER VisitNon contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsDay 3Urologist ConsultationSeen by urologist Schedule ureteral stent placementFollow-up
Prescriptions Antibiotics if infection suspected Scheduling
Day 7Stent Placement~ 30 minutes Recovery and dischargeUreteral stent placed under sedation or anesthesia in ASC Procedure
General anesthesia Duration
Post-Procedure Care
Day 45URS-LL1 hour Stent RemovalGeneral anesthesia Duration
Post-Procedure
Day 48Follow-up VisitPost-operative check for complications KUB to confirm stone fragments clearanceAssessment
Imaging 
Day 75Follow-up CT ScanNon-contrast CT scan for stone-free status Evaluation of residual fragments and ureteral healingImaging
Assessment With Avvio LithotripsyDay 1ER VisitNon contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsDay 3Urologist ConsultationFollow-upIntervention

Seen by urologist AVVIO Microbubbles Cavitation LithotripsyDay 33Follow-Up VisitAssessment
 Post Procedure check in and CT imaging if neededCurrent Standard of CareDay 1ER VisitNon contrast CT scan confirms 8mm stone in proximal ureter Diagnostic Tests
MedicationsDay 3Urologist ConsultationSeen by urologist Schedule ureteral stent placementFollow-up
Prescriptions Antibiotics if infection suspected Scheduling
Day 7Stent Placement~ 30 minutes Recovery and dischargeUreteral stent placed under sedation or anesthesia in ASC Procedure
General anesthesia Duration
Post-Procedure Care
Day 45URS-LL1 hour Stent RemovalGeneral anesthesia Duration
Post-Procedure
Day 48Follow-up VisitPost-operative check for complications KUB to confirm stone fragments clearanceAssessment
Imaging 
Day 75Follow-up CT ScanNon-contrast CT scan for stone-free status Evaluation of residual fragments and ureteral healingImaging
Assessment

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*Data on file
CAUTION – Investigational device. Limited by Federal (or United States) law to investigational use. Avvio Medical, Inc. does not currently offer medical devices for sale or distribution and the company’s technology has not received market clearance status by the U.S. FDA or any other country’s regulatory authority.
MKT-006 Revision Q, September 2025.